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History. Adapalene was approved in 1996 by the U.S. Food and Drug Administration (FDA) for use in the treatment of acne. [citation needed] Available forms.Buy Retin-A. User Reviews for. remedy for external use against acne. The best therapeutic effect from the use of retin-A for reviews is achieved after 8-12.

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Retinoid therapy for acne: A comparative review. We describe and compare the different topical retinoids, tretinoin (all-trans-retinoic acid), isotretinoin.

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